She was one of the clear favorites. She was one of the three women who have three titles this year. She was in peak form since winning the Australian Grand Slam. 
Unfortunately, her fellow Russian with the a difficult surname, Alla Kudryavtseva, beat her 6-2 6-4 in the second round. What made the defeat more shocking was that Kudryavtseva is lowly ranked 154th in the world and has never really made a mark in any of the Grand Slam.
Sharapova's double faults and unforced errors
made it much easier for her compatriot, who was playing all out to beat her. Kudryavtseva really played as if she had nothing to lose, and winning over world no. 3 Sharapova was worth more than winning a Grand Slam.
Something's wrong with the glamour girl in tennis. Whatever it is, only she knows. She has to reflect back after this loss, and work harder even more and be ready for the next Grand Slam.